Atherosclerosis

Discovering links between stress and vascular healthA lifelike illustration of a red artery blocked with yellow plaque as red blood cells get trapped at the blockage.

Atherosclerosis is a disease of the blood vessels that is characterized by constant low-grade inflammation and the formation of dangerous blockages in medium and large vessels, called atherosclerotic plaques. Atherosclerosis is a major cause of cardiovascular disease and death in many countries including United States.

Cardiovascular diseases are closely linked with other conditions such as:

  • metabolic problems, like diabetes;
  • autoimmune disorders, such as Rheumatoid arthritis;
  • neuroimmunological disorders;
  • stress; and
  • unhealthy sleep.

But, the actual ways these factors worsen atherosclerosis are not well understood.

CINID's unique collaboration allows researchers to best investigate interactions between the immune system, vasculature and brain activities. The goal is to better understand how these systems interact, which would ultimately open new avenues to develop therapies and medications.