Currently there are three NIH-sponsored pediatric research studies in our department, all of which treat children who have Down Syndrome and Obstructive Sleep Apnea.
- Study 1: HGN is a study that looks at the effects of Hypoglossal Nerve Stimulation on Cognition and Language in patients with Down Syndrome and persistent Obstructive Sleep Apnea. It involves an implanted medical device being used to treat those in the DS population who are within the ages of 10-21 and have severe Obstructive Sleep Apnea. Participants must have had their tonsils and adenoids removed.
- Study 2: DOSA is a study that allows children with Down Syndrome and persistent moderate to severe Obstructive Sleep Apnea to possibly receive oxygen therapy as a new treatment for their sleep apnea.
- Study 3: TOPS is a study in which children with Down Syndrome and moderate to severe Obstructive Sleep Apnea (who have never had surgery for their sleep apnea), can receive either a standard adenotonsillectomy or a sleep endoscopy-directed personalized surgery, which could possibly benefit participants more than the standard adenotonsillectomy procedure, due to the unique obstructive patterns that a child with Down Syndrome may have.
