 Julie
A. Kerry, Ph.D.
Associate Professor
Lewis Hall, #3152
Office: (757) 446-5663
Email: kerryja@evms.edu
Teaching: Molecular
and Cellular Biology, Cell Biology, Virology and Tumor
Biology
Biomedical Sciences
Program Track:
Molecular Integrative
Biosciences (MIB)
Education
-
B.S., South Australian
Institute of Technology, Australia
-
M.S., South Australian
Institute of Technology, Australia
-
Ph.D., Monash University,
Australia
-
Postdoctoral Training,
University of California, Santa Barbara
Research Interests
Dr. Kerry's studies are
designed to characterize the virus-host cell interactions
required for the replication of human cytomegalovirus (HCMV).
HCMV is a significant human pathogen, causing severe
morbidity and mortality in congenitally infected infants and
immunocompromised individuals. However, despite the growing
problem of HCMV disease, very little progress has been made
in understanding how viral early genes are activated at the
molecular level.
The laboratory focuses on the
assessment of viral and cellular factors involved in HCMV
gene expression. In particular, these studies analyze the
mechanism of action of two important viral transcriptional
regulators: IE86 and pp71. Characterization of these factors
and their interactions with cellular proteins involved in
viral gene regulation will greatly enhance the fundamental
understanding of the regulatory events governing viral gene
expression. These studies may therefore reveal novel
strategies for antiviral therapies designed to inhibit viral
gene expression.
Selected Publications
-
Ciocco-Schmitt, G. M.,
Karabekian, Z., Godfrey, E. W., Stenberg, R. M.,
Campbell, A. E. and Kerry, J. A.
Identification and Characterization of Novel Murine
Cytomegalovirus M112-113 (e1) Gene Products. Virology,
294, 199-208. 2002.
-
McWatters, B. J. P.,
Stenberg, R. M. and
Kerry, J. A. Characterization Of The Human
Cytomegalovirus UL75 (glycoprotein H) Late Gene
Promoter. Virology, 303, 309-316. 2002.
-
Chau, N. H., Vanson, C. D.,
and Kerry, J. A. Transcriptional Regulation of
the Human Cytomegalovirus US11 Early Gene. Journal of
Virology 73:863-870. 1999.
-
Johnstone, R. W., Kerry,
J. A., and Trapani, J. A. The Human
Interferon-Inducible Protein, IFI16, is a Repressor of
Transcription. Journal of Biological Chemistry 273:
17172-17177, 1998.
-
Kerry, J.A., Priddy,
M.A., Staley, T.L., Jones, T.R. and Stenberg, R.M. The
role of ATF in regulating the human cytomegalovirus DNA
polymerase (UL54) promoter during viral infection.
Journal of Virology 71:2120-2126, 1997.
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